Membrane fluidity is largely determined by: A. saturation of fatty acid components of phospholipids. B. percentage of protein in the membrane. C. permeability of the membrane to water. D. attachments to the cytoskeleton.
A. saturation of fatty acid components of phospholipids
fluidity of a membrane determined by the ratio of (poly)unsaturated to saturated fatty acyl chains of its phospholipids influences the effectiveness of glucose transport by insulin-independent glucose transporters (GLUTs) and the insulin-dependent GLUT4, and from the prediabetic stage on a shift from unsaturated towards saturated fatty acyl chains of membrane phospholipids directly induces a decrease in glucose effectiveness and insulin sensitivity.
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