Question

Which is the most reactive nucleophile in acetone? F- Cl- Br- I-

Which is the most reactive nucleophile in acetone?

F-

Cl-

Br-

I-
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Homework Answers

Answer #1

Acetone is non polar solvent.

Acid stregth of halo acids increases in the order.

(weakest acid) HF < HCl < HBr < HI (strongest acid)

Basicity of corresponding conugate based is,

Strongest F- > Cl- > Br- > I- (Weakest)

Stongest base caanot act as good nucleophilicity. Basicity hampers nucleophilicity.

Iodide ion I- is weakest base as it is a conjugate base of strongest haloacid Hydroiodic acid HI.

Iodide ion I- hence will be a strongest nucleophile in acetone.

Answer option : I-.

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