Question

Grignard reaction questions?

a. Give equations for a detailed procedure showing the conversion of 1-bromoheptane to 3-decanol using a Grignard reaction.

b. Why is it necessary to clean and cut the magnesium ribbon into small pieces in the preparation of Grignard reagent?

c. Why care must be taken to have the reagents and apparatus completely dry when a Grignard reaction is performed. What could be a major side reaction if water were present?

d. Ethanol is often present in solvent-grade diethyl ether. If this grade, rather than anhydrous were used, what effect would the ethanol have on the formation of the Grignard reagent?

e. Why is it necessary to acidify the mixture (addition of HCl) after the completion of Grignard reaction?

Thank you so much.

Answer 1