Question

This spring our newborn lambs suffered from a bout with coccidiosis (intestinal infection caused by single-celled protozoa called coccidia). Treatment involves giving them oral doses of a coccidiostat for five consercutive days. The compound we used was amprolium ( 278.8 g/mol) which is sold as a 9.6% w/v solution. A 100lb lamb revieced 4.75 mL of the solution once a day for five days.

1. What is the molar concentration of the amprolium solution?

2. How many milimoles of amprolium were delivered to a 100lb lamb each day?

Part Two:

1. The TRIS buffer system is often used in biochemical labs. The pKa for the TRIS-H⁺/TRIS conversion is 8.1. I have prepared 1 L of 50 mM TRIS buffer at pH 7.75. What are the concentrations of TRIS-H⁺ and TRIS in the buffer? Provide anwsers to 3 signifigant digits in mM.

TRIS-H⁺ = 34.6 mM

TRIS = 15.4 mM

2. Monosodium glutamate (MSG) was added to baby food for years in order to make food taste better to the person providing the food (babies don't care, parents do). MSG is the monosodium salt of glutamic acid. The pKa values for glutamic acid are 2.2, 4.25, and 9.7. Draw the predominate structure of MSG at pH4, placing the sodium cation with the most appropriate ionizable functional group.

Answer 1