Question

1.If we can obtain protein structures from x-crystallography and NMR why we need programs to solve the protein the structure?

2. why solving the 3D structure of protein is important?

Answer 1

1. Although protein structure can be deduced from X-ray crystallography and NMR, we need programs to solve for protein structure as these are used to study the various possible and present in the system secondary interactions. The interactions are well studies by 3D analysis of proteins which help us understand the folding in protein sequences. Also a huge list of library of proteins can be generated by the software absolutely in theoretical manner without rnning a large number of experiments.

2. Solving 3D structure of protein helps us study the various secondary and tertiary interactions that might be present in the structure upon folding of protein chains. These thus can be used to study the functions related to it and modify the structure in a better and effective manner depending upon the end usage.