For the substituent in this experiment that was found to be least activating, explain why bromination took place at the position on the ring indicated by the experimental results.
Experiment 40 (relative reactivities of several aromatic compounds) out of the Microscale Approach to Organic Laboratory Techniques.
The -NHCOCH3 group is a less powerful ortho,para directing
group than -NH2 due to the presence of the electron
withdrawing carbonyl group,which renders the aromatic ringless
electron-rich. Electrophilic substitution by bromine is
stilldirected electronically to theortho and para positions on the
ring.the acetamido group,-NHCOCH3, however, effectively blocks the
ortho positions by steric hindrance. For thesereasons, only para
substitution is usually observed.
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