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solve the michaelis-menten equation for km when vo=vmax/2. what does this reveal about the relationship between...

solve the michaelis-menten equation for km when vo=vmax/2. what does this reveal about the relationship between the [substrate] and the enzyme? Generally, what does it mean when the Km is high? low?

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Answer #1

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# Km is [S] at which ½ Vmax of the enzyme is attained.

# When Km is high, the enzyme would require relatively higher [S] to reach its saturation. It also means that the enzyme has lower affinity for that substrate.

# When Km is low, the enzyme would require relatively lower [S] to reach its saturation. It also means that the enzyme has higher affinity for that substrate.

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