Question

Could 2-proponal be used as a solvent in a gringnard reaction? if not, please explain what...

Could 2-proponal be used as a solvent in a gringnard reaction? if not, please explain what other reagents could replace the ether and why

Homework Answers

Answer #1

Grignard reaction is a reaction between RX and Mg metal. In this reaction RMgX is formed in which alkyl group R- group is very strong hydrogen capturer. It reacts with any protic solvent to pick up hydrogen giving alkane RH. So the desired reaction fails. To avoid this aprotic solvent like dry (H2O free) ether is used. It is therefore if you want to replace ether you have to use solvent such as it is aprotic. Tetrahydrofuran THF can be used instead of ether.

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