Question

Could 2-proponal be used as a solvent in a gringnard reaction? if not, please explain what...

Could 2-proponal be used as a solvent in a gringnard reaction? if not, please explain what other reagents could replace the ether and why

Homework Answers

Answer #1

Grignard reaction is a reaction between RX and Mg metal. In this reaction RMgX is formed in which alkyl group R- group is very strong hydrogen capturer. It reacts with any protic solvent to pick up hydrogen giving alkane RH. So the desired reaction fails. To avoid this aprotic solvent like dry (H2O free) ether is used. It is therefore if you want to replace ether you have to use solvent such as it is aprotic. Tetrahydrofuran THF can be used instead of ether.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
If, by mistake, a chemist used 100% ethanol rather than diethyl ether as the reaction solvent,...
If, by mistake, a chemist used 100% ethanol rather than diethyl ether as the reaction solvent, would the Grignard synthesis still proceed as expected?
What product would result from the reaction of (R)-2-bromooctane with – CN, in a DMSO solvent?...
What product would result from the reaction of (R)-2-bromooctane with – CN, in a DMSO solvent? What is the stereochemistry of the product? Explain your answer to the stereochemistry question by writing a detailed mechanism for this reaction. Why is DMSO a good solvent for this reaction? (2 points)
Grignard reaction questions? a. Give equations for a detailed procedure showing the conversion of 1-bromoheptane to...
Grignard reaction questions? a. Give equations for a detailed procedure showing the conversion of 1-bromoheptane to 3-decanol using a Grignard reaction. b. Why is it necessary to clean and cut the magnesium ribbon into small pieces in the preparation of Grignard reagent? c. Why care must be taken to have the reagents and apparatus completely dry when a Grignard reaction is performed. What could be a major side reaction if water were present? d. Ethanol is often present in solvent-grade...
Grignard reaction questions? a. Ethanol is often present in solvent-grade diethyl ether. If this grade, rather...
Grignard reaction questions? a. Ethanol is often present in solvent-grade diethyl ether. If this grade, rather than anhydrous were used, what effect would the ethanol have on the formation of the Grignard reagent? b. Why is it necessary to acidify the mixture (addition of HCl) after the completion of Grignard reaction? c. Why is it necessary to clean and cut the magnesium ribbon into small pieces in the preparation of Grignard reagent? Thank you
Which of these TLC solvent systems listed below is the most polar and explain why? 1:2...
Which of these TLC solvent systems listed below is the most polar and explain why? 1:2 (v:v) Hexane:diethyl ether 2:1 (v:v) Hexane:diethyl ether 1:3 (v:v) Hexane:diethyl ether 3:1 (v:v) Hexane:diethyl ether 1:1(v:v) Hexane:diethyl ether             (a) The Rf of compound B is? Circle the correct answer. 0.47 0.54 0.60 0.64 0.69 0.78 0.82 1.00 (b) Looking at the TLC plate in 4(a), which compound interacts least with the stationary phase? Explain (4 pts) Would you need to use a more...
Ethyl acetate is another common organic solvent used in the type of TLC experiment you performed:...
Ethyl acetate is another common organic solvent used in the type of TLC experiment you performed: it has a higher molecular weight and boiling point than either petroleum ether or diethyl ether, and is more polar than them as well. If ethyl acetate had been used as the mobile phase for a TLC analysis of F and AF, how would their Rf values compare to those found using the 1:1 solvent mixture you used? That is, predict how the behavior...
Tony was working in a laboratory. He needed to work up a reaction that used concnetrated...
Tony was working in a laboratory. He needed to work up a reaction that used concnetrated sulfuric acid. Tony's boss told him to use diethyl ether but he mistakenly used ethyl acetate. Tony mixed the ethyl acetate and the acid/aqueous layer and was waiting for the two to separate but they never did. What happened to the ethyl acetate under the strongly acidic conditions? Why would diethyl ether have been a better solvent?
We used 85% phosphoric acid in this reaction. What other acids could have worked to achieve...
We used 85% phosphoric acid in this reaction. What other acids could have worked to achieve similar results? Explain your answer.
1. Draw the major products only expected from the reaction of 2-bromo-3-methylpentane with each of the...
1. Draw the major products only expected from the reaction of 2-bromo-3-methylpentane with each of the following: A. CH3CH2O- B. (CH3)3CO- C. CH3CH2OH 2. Starting with an appropriate alkyl halide and using any other needed reagents, how could you synthesize the following? A. butyl sec-butyl ether B. CH3COCH2CH3 || O C. (CH3)3CCH=CH2
1. Draw the general reaction that occurs between benzaldehyde and acetophenone and propose a mechanism for...
1. Draw the general reaction that occurs between benzaldehyde and acetophenone and propose a mechanism for the formation of chalcones from these reagents in the presence of NaOH. 2. a. Why does the enolate ion preferentially react with the benzaldehyde and not with the acetophenone in this reaction? b. Briefly explain the advantages of eliminating the reaction solvent. c. Can you think of any complications that may result as a consequence of eliminating the reaction solvent?
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT