Question

1. A metabolic reaction A↔ B has ∆G°’ = 7.5 kJ/mol This metabolic reaction takes place in solution in the human body and there are no solids or gases involved. a) Calculate Keq for the reaction at 25°C b) Calculate ∆G for the reaction at 37°C, when [A] = 0.5 mM and [B] = 0.1 mM. Is the reaction spontaneous under these conditions? c) How can the reaction’s direction in the cell be changed without changing the temperature? Be logical and explicit. In principle there are three different ways of doing this.

Answer 1

At constant temperature, the reaction's direction in the cell be changed by changing the concentration of either reactant or product according to Lechetllier's principle.

If we increase the concentration of A, then there will be more reactant then the uxn moves foreward to the product side

At constant temperature, the reaction's direction in the cell be changed by changing the concentration of either reactant or product according to Lechetllier's principle.

If we increase the concentration of A, then there will be more reactant then the uxn moves foreward to the product side