Question

The amino acid, lysine, has three titratable groups with pKa values of 2.16, 9.06, and 10.54....

The amino acid, lysine, has three titratable groups with pKa values of 2.16, 9.06, and 10.54. Sketch the titration curve that would result if the completely deprotonated form of this amino acid was titrated with the HCl. Label all the components of the titration curve.

Homework Answers

Answer #1

Before starting to titrate Lysine K, this titration are going to be done crushioning its ions and conuter-ions to make more simple the curve.

.The relationship among pH and pK is the Henderson Hanselbach ecuation applied to calculate pH from pK.

In the equivalent points, [protonated specie]=[unprotonated specie] and pH=pKa

    ​

The [HCl] concentration of the graphic is the one from titrated solution and the pH is from the titrated solution

   

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
1. Based on pKa values, which amino acid side chains are easiest to protonate and deprotonate...
1. Based on pKa values, which amino acid side chains are easiest to protonate and deprotonate at cellular pH (7.4)? (Choose all that apply) Aspartic Acid Histidine Lysine Serine Arginine Glutamic Acid Cysteine Tyrosine 2. At pH 7.4, which of the amino acid sidechains or R-groups below will be mostly deprotonated? (Chose all that apply) Glutamatic Acid Aspartic Acid Arginine   Tyrosine Serine   Lysine   Histidine Cysteine 3. Acetyltransferase enzymes modify a lysine side chain with an acetyl group. Titration of the...
Sketch the titration curve that would result if the fully unprotonated form of cysteine were titrated...
Sketch the titration curve that would result if the fully unprotonated form of cysteine were titrated with HCl. Label midpoints, equivalence points and indicate which part of the titration corresponds to each of the specific pKa values of cysteine
2.The titration curve of alanine shows the ionization of two functional groups with pKa values of...
2.The titration curve of alanine shows the ionization of two functional groups with pKa values of 2.34 and 9.69, corresponding to the ionization of the carboxyl and the protonated amino groups, respectively. The titration of di-, tri-, and larger oligopeptides of alanine also shows the ionization of only two functional groups, although the experimental pKa values are different. The trend in pKa values is summarized in the table. Amino acid or peptide pK1 pK2 Ala 2.34 9.69 Ala-Ala 3.12 8.30...
1. Look up the structure of citric acid and the pKa values associated with disassociation of...
1. Look up the structure of citric acid and the pKa values associated with disassociation of each proton. a) Write the full disassociation (overall and each step) reaction starting with the fully protonated acid and ending with the fully deprotonated salt. b) Sketch a titration curve (y axis pH and x axis equivalents of base) identify each pka on the graph and note the acid and the salt at each step (similar to the graph for phosphate in the notes)...
Consider the amino acid lysine (H3Lys2+ in the fully protonated form) which has pKa1 = 2.04,...
Consider the amino acid lysine (H3Lys2+ in the fully protonated form) which has pKa1 = 2.04, pKa2 = 9.08, and pKa3 = 10.69. a. What is the charge on the principal species at pH 7.4 (blood)? Circle one of +2 +1 0 -1 -2 b. What is the charge on the principal species at pH 10.0? Circle one of +2 +1 0 -1 -2 c. Calculate the fraction of the total lysine which exists in the neutral form (HLys0) at...
Consider a 0.317L solution of the amino acid glutamic acid(0.575M), which has the alpha carboxylic group...
Consider a 0.317L solution of the amino acid glutamic acid(0.575M), which has the alpha carboxylic group (pKa=2.10), an alpha amine group(pKa=9.47), and a carboxylic acid group in the side chain(pKa=4.10). If the titration is started at a very low pH, how many litres of 2.27M NaOH would you need to addto reach the isoelectric point of the amino acid?
3-Fluorophenol has a pKa of 8.40. 4-Nitrophenol has a pKa of 7.16. 3-Chlorobenzoic acid has a...
3-Fluorophenol has a pKa of 8.40. 4-Nitrophenol has a pKa of 7.16. 3-Chlorobenzoic acid has a pKa of 3.82. You will need the following information: The pKa of HCl is –7; pKa of carbonic acid is 6.52 and the pKa of water is 15. a) You have a mixture of 3-fluorophenol and 4-nitrophenol that you wish to separate by extraction. The mixture is dissolved in methylene chloride. Why would reacting the mixture with an aqueous solution of NaHCO3 NOT separate...
Calculate the pH of solutions with a [H+] of 6.4 x 10-12M Calculate the [H+] and...
Calculate the pH of solutions with a [H+] of 6.4 x 10-12M Calculate the [H+] and [HO-] for a pH 7.4 solution: [H+] = [HO-] = 3. What is the pH of a 0.3M solution of acetic acid? (the pKa for acetic acid is 4.75) 4. Sketch a drawing or use Excel or other graphing software to draw a titration curve for histidine. Label the graph with pI, pKa, and equivalence point. Would phenylalanine be a good physiologic buffer? Why?...
There are two codons for the amino acid lysine: 5’-AAA-3’ and 5’-AAG-3’. Which of the following...
There are two codons for the amino acid lysine: 5’-AAA-3’ and 5’-AAG-3’. Which of the following tRNA anticodon sequences would be able to recognize both of these codons? Group of answer choices 5’-UUU-3’ 5’-UUC-3’ 5’-CUU-3’ 5’-IUU-3’ Question 471 pts There are six codons for the amino acid arginine. Three of these codons are: 5’-CGC-3’ 5’-CGU-3’ 5’-CGA-3’ Which of the following anticodons would be able to recognize all three of these codons? Group of answer choices 5’-ACG-3’ 5’-GCG-3’ 5’-UCG-3’ 5’-ICG-3’ 5’-GCI–3’...
An experiment has a single factor with five groups and three values in each group. In...
An experiment has a single factor with five groups and three values in each group. In determining the​ among-group variation, there are 4 degrees of freedom. In determining the​ within-group variation, there are 20 degrees of freedom. In determining the total​ variation, there are 24 degrees of freedom.​ Also, note that SSA= 96, SSW=160, SST=256, MSA=24, MSW=8, and FSTAT=3. Complete parts​ (a) through​ (d).Click here to view page 1 of the F table. a. Construct the ANOVA summary table and...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT