Question

Suppose the glycolytic enzyme, GAPDH, were able to bind ADP and convert GAP all the way...

Suppose the glycolytic enzyme, GAPDH, were able to bind ADP and convert GAP all the way to 3PG, instead of 1,3-BPG. How would this affect the equilibrium for the reaction ?

Science   Chemistry   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Answer

Normally, GADPH binds to GAP and converts it to 1.3-BPG which then is converted to 3PG by PGK.

This reaction, GAPà1,3-BPGà3PG is catalyzed by two enzymes which has different parts to play in glycolysis.

Conversion of GAP is regulated by concentration of GAP and NAD+ and this reaction is pulled by next exergonic reaction i.e. 1,3-BPGà3PG.

If the proposed pathway should happen, all the GAP would be directly converted to 3PG without even giving chance to slightly control the pathway. GAP inhibits previous aldolase reaction and that would be lost by proposed pathway.

In gluconeogenic pathway PGK catalyzes the reverse reaction, it would be catalyzed by GADPH only.

If the proposed mechanism is to be true, it would have been non-reversible reaction and equilibrium would be on 3PG side. The concentration of 3PG would have been higher.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
1.Suppose that two proteins, A and B, can associate with each other to form a complex.  ...
1.Suppose that two proteins, A and B, can associate with each other to form a complex.   You measure the dissociation constant at several different temperatures and find that as you heat up the sample, the Kd decreases. Does this mean that binding of A and B becomes more favorable or less favorable as the temperature increases? 2.Calculate the ΔG for ATP hydrolysis in a cell in which the [ATP]/[ADP] ratio had climbed to 100_1, while the Pi concentration remained at...
Nurse practitioners have to be supervised by physicians. As a result, they were complements. a. Suppose...
Nurse practitioners have to be supervised by physicians. As a result, they were complements. a. Suppose that an increase in malpractice insurance premiums raised physician costs. Show how this would affect the equilibrium price and quantity of physician services. On all graphs, label both the market (e.g., physicians or nurse practitioners) and the two axes. b. On a new graph, show how the change in the physician market from part a above, will affect equilibrium price and quantity in the...
Suppose that the labor supply of party clowns in Moscow is given by: w = 10...
Suppose that the labor supply of party clowns in Moscow is given by: w = 10 + 0.2QS. The labor demand in the market is described by: w = 40 – 0.2QD. In these equations, w represents the hourly wage, and Q represents the quantity of clowns. a. (4 points) Assuming this is a competitive labor market, solve for equilibrium in the market. Sketch a simple diagram of the market, label the welfare areas, and solve for the welfare (surplus)...
7) Suppose your crystal's density is 2.312 g/cm3. Use conversion factors to convert this to mg/μl...
7) Suppose your crystal's density is 2.312 g/cm3. Use conversion factors to convert this to mg/μl Show all your work and all your units throughout. Now to the doctor's office: 8) I have come to see you, the doctor, because I was feeling a bit ill. The first thing the nurse did was look at me and see I had a large growth in my neck. “Wow!” she said. “How long has this been going on?” “For a couple of...
62. As noted in the article about trading pits, a. futures pits in Chicago were closing...
62. As noted in the article about trading pits, a. futures pits in Chicago were closing down. b. futures pits in New York were closing down. c. floor trading on the New York Stock Exchange were closing down. d. All of the above. e. Only A and B of the above. 63. Which of the following are among the lessons that we can reasonably draw from the collapse of Continental Illinois? a. The aggressive pursuit of commercial loans was doomed...
Homeplate Lexi Taylor looked out the window of her Rexburg apartment and marveled at how her...
Homeplate Lexi Taylor looked out the window of her Rexburg apartment and marveled at how her life had changed in the past few months. Since launching Homeplate a little over a year ago, she had grown from a one-person operation preparing meals in the local YMCA kitchen to a fast growing meal preparation and delivery service, with nearly 3,000 regular customers and strong growth and profit potential. Lexi had gone through raising a seed round of capital and was now...
1.) True or False? For all societies, resources are scarce, and technology is limited, while people’s...
1.) True or False? For all societies, resources are scarce, and technology is limited, while people’s wants and needs for goods and services seem to be unlimited. (2 points) 2.) (1 point) Adam Smith’s “invisible hand” refers to a.) the subtle and often hidden methods that businesses use to profit at consumers’ expense. b.) the ability of free markets to reach desirable outcomes, despite the self-interest of market participants. c.) the ability of government regulations to benefit consumers, even if...
Outline and answer all discussion questions following case description in details. (Do not attempt to solve...
Outline and answer all discussion questions following case description in details. (Do not attempt to solve if you can not fulfill all the requirements!!!!) THE ENERGY BAR INDUSTRY In 1986, PowerBar, a firm in Berkeley, California, single-handedly created the energy bar category. Positioned as an athletic energy food, it was distributed at bike shops and events that usually involved running or biking. The target segment was the athlete who needed an efficient, effective energy source. Six years later, seeking to...
Please do not attempt to solve if you can not answer all!!! THE ENERGY BAR INDUSTRY...
Please do not attempt to solve if you can not answer all!!! THE ENERGY BAR INDUSTRY In 1986, PowerBar, a firm in Berkeley, California, single-handedly created the energy bar category. Positioned as an athletic energy food, it was distributed at bike shops and events that usually involved running or biking. The target segment was the athlete who needed an efficient, effective energy source. Six years later, seeking to provide an alternative to the sticky, dry nature of the PowerBar, a...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old man of Scandinavian descent was rushed to the Emergency Room of your local hospital after a family member discovered him unconscious in his home. The woman who dialed “911” told the dispatcher that the man, her brother, was the local librarian of the past 10 years and had no spouse or children. She reported that they had spoken the day before, and he had...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT