Question

what is the purpose of lab of Benzoin Condensation of Furfural. Please right one to two...

what is the purpose of lab of Benzoin Condensation of Furfural. Please right one to two paragraphs as an introduction

Homework Answers

Answer #1

Benzoin Condensation is a coupling reaction between two aldehydes that allows the preparation of α-hydroxyketones. Thiamine is responsible for biosynthesis of acyloin-like compounds. In the first step of reaction, the cyanide anion (as sodium cyanide) reacts with the aldehyde in a nucleophilic addition. Rearrangement of the intermediate results in polarity reversal of the carbonyl group, which then adds to the second carbonyl group in a second nucleophilic addition. Proton transfer and elimination of the cyanide ion affords benzoin as the product. This is a reversible reaction.

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