How does N-acetylcysteine (NAC) scavenge reactive oxygen species?
N-acetylcysteine (NAC)
N-acetylcysteine (NAC) is an aminothiol and synthetic precursor of intracellular cysteine and glutathione and is an important antioxidant. Due to the antioxidative action and free radical scavenging property of NAC, it results in increasing intracellular glutathione levels. NAC also has reducing property through its thiol-di-sulphide exchange activity.
Reactive oxygen species is the oxygen having free radical. NAC due to its antioxidative action takes the free radical of the Oxygen with the help of aminothiol and intracellular synthetic precursor cysteine.
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