Question

Explain the importance of the citric acid cycle? How does NADH and FADH2 contribute to the citric acid cycle?

Answer 1

The citric acid cycle is the pathway for the oxidation of the two carbon units and it is also a major pathway for the interconversion of metabolites arising from transamination and deamination of amino acids, providing the substrate for the amino acid synthesize by transamination as well as for the gluconeogenesis and fatty acid synthesis

this cycle is also well known as the kerb cycle .The citric acid cycle is an aerobic universal Acetyl~coA catabolic cycle. It is a central metabolic cycle.

FADH2 and NADH are created form FAD and NAD+ by the oxidation and reduction reactions in the kerb cycle

These two compounds are used to move electrons into the electron transport chain, the final stage of respiration. It is at this stage that most of the energy is created and released from the mitochondria