Question

Explain observed steric effects in elimination reactions.

Explain observed steric effects in elimination reactions.

Homework Answers

Answer #1

extremely bulky substrate

when steric hindrance increasing around the α-carbon while E1 reaction proceed due to no back side attacking

when steric hindrance increasing in base, that time base act poor nucleophile

extremely bulky base

the proton we remove proton from CH3 to form low Zaitsev product or less substituted product.

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