Question

What role does the GTPase activity of G proteins play within signaling pathways?

	It produces cGMP, a second messenger.
	It terminates the signal of the G protein.
	It increases the signal of the G protein as long as GDP remains bound.
	It causes permanent inactivation of the G protein.

Answer 1

Answer:- It produces cGMP, a second messenger.

GTPases are hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP).

GTPase activity of G-proteins leads to:

	1. Stimulating the activity of enzymes by producing energy.
	2. Production of cGMP as a second messenger.
	3. synthesis of GTP as an energy source.
	4. hydrolysis of GTP returning the G protein to its original level of activity before activation by the endogeneous lignand.