Question

Consider the Na+/K+-ATPase to be present in a membrane with the following conditions: Na+ concentration inside,...

Consider the Na+/K+-ATPase to be present in a membrane with the following conditions: Na+ concentration inside, 50mM, outside, 250mM; K+ concentration inside, 70mM, outside, 5 mM; at 298K with the voltage being 50mV lower in the interior.

3Na+(in) + 2K+(out) + ATP + H2O ↔ 3Na+(out) + 2K+(in) + ADP + Pi

Calculate the free-energy difference for transporting Na+ from the inside to the outside.

a. +4.1 kJ/mol

b. +9.0 kJ/mol

c. -0.7 kJ/mol

d. +0.7 kJ/mol

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