Question

Calculate the volume (in mL) per dose for 400. mg/mL amoxicillin to deliver two doses per day at 40.0 mg/(kg⋅day) for a 22.0 pound patient. 2.20 pounds = 1 kg.

Group of answer choices

0.500 mL/dose

2.50 mL/dose

33.1 mL/dose

0.400 mL/dose

10.0 mL/dose

Answer 1

Given data:

Patient weight = 22.0 pound, 2.20 pound = 1 kg

Dose per day = 40.0 mg / kg.day

Concentration of amoxicillin = 400 mg/mL

Solution:

1. 22.0 pound = 22.0 pound x (1kg . 2.20 pound) = 10 kg

2. Two dose per day = (40.0 mg / kg⋅day) x 10 kg = 400mg / day

3. One dose = 400 mg / day x (1 day / 2 dose) = 200 mg / dose

4. Volume (in mL) per dose = (200 mg / dose) / (400 mg/mL) = 0.500 mL / dose

Hence, 1^st option 0.500 mL / dose is the volume (in mL) per dose for 400 mg/mL amoxicillin.