Question

Suppose this reaction proceeds as expected to give a mixture of diastereomers. How will that affect the observed mp?Will you see 2 distinct mp’s that correspond to the 2 mp’s shown in the handout? Will you see a mp that’s smack dab between the 2 literature mp’s?(Hint: think back to colligative properties).

Answer 1

1. Diastereomers: Which are non-superimposable non mirror images.They posses different physical properties and chemical properties. Melting point is one of the physical properties so it should varry for the diastereomers.

2. Melting point of the diastereomeric mixture is always lower than that of the pure Diastereomer. So that we can observe lower range of melting point.

3. Mixtures of different substances generally melt over a range of temperatures. So that we can not see smack dab between the 2 literature melting points.