Question

Acetylating agents such as acetic anhydride react preferentially with primary amines, iodoacetate reacts preferentially with sulfhydryl groups, and ATP-dependent kinases preferentially add a phosphoryl group to side-chain hydroxyl or phenolic −OH groups. Which amino acid side chains, or main chain groups, in a polypeptide are most likely to be modified by treatment with:

Part A

acetic anhydride

Check all that apply.

Check all that apply.

Proline

Lysine

Asparagine

Glutamine

Arginine

N-terminal amine

Answer 1