Question

A certain macromolecule P has four identical sites in a linear array for the binding of a small molecule A. Prepare a table listing all species with half of the sites occupied (species woth two occupied ajd two unoccupied sites) and their statistical weights for the following cases:

a) The sites are independent.

b) Nearest-neighbor interactions are present.

c) Binding to one site excludes the binding to a site immediately adjacent to it.

d) Give also, for part (b), an expression for the concentration ratio [PA4]/[PA2]

Answer 1