Question

Calculate the pI of the following peptides, suppose the pKa of amino acid does not change...

Calculate the pI of the following peptides, suppose the pKa of amino acid does not change after formation of peptide bonds, what is the net charge of each at pH=3.8, pH = 8 and pH =11?

A) Glu-His-Trp

B) Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly

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