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8.3 Compare phosphatidylcholine and a ganglioside such as GM1. Explain the significance of the structural differences...

8.3 Compare phosphatidylcholine and a ganglioside such as GM1. Explain the significance of the structural differences with respect to the functional roles of these molecules. (minimum 100 words)

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Answer #1

Phosphatidylcholine is major component of biological membranes and these are phospholipids that incorporate choline as head group.these are mjor constituents of cell membrane and pulmonary sutfactant and commomly found in explasmic or outer leaflet of cell membrane. Lecithin extracts consists of mixture of phosphatidylcholine and other compunds , these are used in dissolution studoes of highly lipophilic durgs.

usually these phospholipids contains one saturtaed fatty acid such as hexa deconoic acid, margaric acid .It also contains unsaturated fatty acid such as oleic acid.

GM1 is a prototype ganglioside and contains one sialic acid residue. GM1 is can impact the neuronal plasticity and repair machanisms and release the neurotrophins in the brain.

ganglioside GM1 is a glycosophingolipid or oligoglycosylceramide with one or more sialic acids linked on the sugar chainn.

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