Question

Topicity is the relation between two atoms or groups within a molecule. If atoms or groups are equivalent, the molecule or bonds of a molecule can be rotated so that they are indistinguishable. If they are enantiotopic they are mirror images of each other but not equivalent. If they are diastereotopic they are connected in the same fashion but not equivalent or enantiotopic. If they are constitutional heterotopic, they are connected differently in a molecule.

Answer whether atoms or groups of the given topicity are indistinguishable by NMR (symmetric environment) and/or by organisms (asymmetric environment).

Equivalent atoms or groups are indistinguishable by organisms.	Answer 1Choose...truefalse
Diastereotopic atoms or groups are indistinguishable by organisms.	Answer 2Choose...truefalse
Constitutional heterotopic atoms or groups are indistinguishable by organisms.	Answer 3Choose...truefalse
Enantiotopic atoms or groups are indistinguishable by organisms.	Answer 4Choose...truefalse
Enantiotopic atoms or groups are indistinguishable by NMR.	Answer 5Choose...truefalse
Constitutional heterotopic atoms or groups are indistinguishable by NMR.	Answer 6Choose...truefalse
Equivalent atoms or groups are indistinguishable by NMR.	Answer 7Choose...truefalse
Diastereotopic atoms or groups are indistinguishable by NMR.

Answer 1

1. equivalent atoms or groups are indistinguishable by organisms. Answer true
2. Diastereotopic atoms or groups are indistinguishable by organisms. Answer false
3. Constitutional heterotopic atoms or groups are indistinguishable by organisms. false
4. Enantiotopic atoms or groups are indistinguishable by organisms. Answer false
5. Enantiotopic atoms or groups are indistinguishable by NMR. Answer true
6. Constitutional heterotopic atoms or groups are indistinguishable by NMR. Answer false
7. Equivalent atoms or groups are indistinguishable by NMR. Answer true
8. Diastereotopic atoms or groups are indistinguishable by NMR. Answer false