Question

Please mark the following statements true or false.

Correct the false statements using minimal changes.

1) A transition state analogue enhances the activity of the enzyme when bound to it.

2. In the induced-fit model, the active site of the enzyme changes its conformation to fit the substrate and its transition state.

3. The Enzyme-Substrate complex must form before the enzyme-catalyzed reaction can take place.

4. Enzyme reduces the energy of the transition state, thus accelerate reaction.

Answer 1

1. It is true. As transition state is the transitory of molecular structure in which molecule is not longer a substrate bur not yet a product.the transition is the state corresponding to highest energy alOng the reaction cordinate

2.it is true.

3.it is false. The enzyme substrate complex is formed when enzymes bind with the substratw. It is the transient state between substrate and product formed.

4.it us false as enzymes lowers the activation energy which increases the speed of the reaction thus increases the acceleration.