Question

Would trituration or recrystallization be a more effective method to purify synthesized guaifenesin?

Would trituration or recrystallization be a more effective method to purify synthesized guaifenesin?

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Answer #1

Recrystallization would be a very more effective method than the trituration method for the purification of synthesized Guaifenesin. This is because all the impurities trapped in the crystal in the trace amount could not be removed through the trituration technique because in this method, the synthesized compound is not dissolved in the solvent while in recrystallization technique, the synthesized compound is recrystallized by completely dissolving in the pure solvent or mixture of solvent.

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