Question

Explain why a mutation in the case of Tom who had a mutation in LDH gene would result in a dysfunctional Cori Cycle with low energy. Specify direction and pathways.

Answer 1

Tomato is an model for experimental study belong to solanaceae family and conserved genetic organization mutant population in Microsoft a dwarf, and rapid growth variety.it is necessory to see the visible phenotype of mutant, and the study in genome information.

Lactate dehydrogenase deficiency mutation in LDH gene and due to this fatigue, tissue damage etc.

In Cori cycle lactate is produced by the anaerobic glycolysis in muscles and transported to liver and converted to glucose then return to the muscles and back to lactate but due to mutation this lactate is not formed. And affect on energy and dysfunction Cori cycle and with low energy.