Question

Molecular Biology and Biochemistry

1. A DNA strand which is used as the template for transcription is known as the ________.

1. leading strand
2. sense strand
3. antisense strand
4. lagging strand
5. coding strand

2. Sickle cell disease results from a point mutation of the __________.

1. α-globin of hydrophilic amino acid for a hydrophobic amino acid
2. β-globin of histidine for glycine
3. β-globin of valine for glutamate
4. γ-globin of proline for tyrosine
5. γ-globin of glutamate for guanine

3. Which of the following molecules has RNA-dependent DNA polymerase activity?

1. DNA polymerase I
2. DNA polymerase III
3. Ligase
4. Telomerase
5. RNA polymerase

4. Which of the following statements about hemoglobin is/are correct?

1. Hemoglobin binds oxygen reversibly.
2. The most abundant form of hemoglobin in human adult is α₂β₂.
3. Hemoglobin switches from its T state to R state in low pH environment.
4. A molecule of hemoglobin contains four protein chains, four heme groups and four irons.

1. (1) only
2. (3) and (4) only
3. (1), (2) and (4) only
4. (2), (3) and (4) only
5. (1), (2), (3) and (4)

Explanation is not necessary, the sooner the better. Thank you.

Answer 1

1)

DNA strand which is used as the template for transcription is known as the ANTISENSE STRAND.
option C is correct

2)

Sickle cell disease results from a point mutation of the  β-globin of valine for glutamate
​​​​​​​option C is correct

3)

Telomerase is an RNA-dependent DNA polymerase, meaning an enzyme that can make DNA using RNA as a template.  
option D is correct

4)

Hemoglobin binds oxygen reversibly.
The most abundant form of hemoglobin in human adult is α2β2.
A molecule of hemoglobin contains four protein chains, four heme groups and four irons.

Hemoglobin switches from its R state to T state in low pH environment.

So the correct statements are (1), (2) and (4) only
which is (option C)