Question

Mutation of chromodomain would inhibit binding to which histone modification?

Mutation of chromodomain would inhibit binding to which histone modification?

Homework Answers

Answer #1

The chromodomain is found in those proteins which are bound into the methylated histone protein. This protein is responsible for methylation in the histone protein. When there is found mutation in the chromodomain, then this protein is not able to modufy the histone protein into tightly packed form. Because this protein can not transfer the methyl group to the histone protein.

The histone methylation is inhibited by the mutation in chromodomain region.

---

please rate high..

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
What histone modification causes chromatin to relax/decondense? What enzyme adds this modification? What enzyme removes it?
What histone modification causes chromatin to relax/decondense? What enzyme adds this modification? What enzyme removes it?
I identified a new histone modification in my laboratory. How do I determine all sites on...
I identified a new histone modification in my laboratory. How do I determine all sites on the human genome where this modification is present?
Which of the following would not affect transcription in prokaryotic cells? A. Mutation of promoters. B....
Which of the following would not affect transcription in prokaryotic cells? A. Mutation of promoters. B. Mutation of histone acetylases. C. Mutation of operators. D. Inactivation of repressors. E. Mutation of RNA polymerase. Ubiquitylation of a cyclin marks the protein for destruction in proteasomes. True False Of the two kinds of cell death (necrosis and apoptosis), necrosis is an important part of normal developmental processes. True False Help all of them please
If you discovered a new histone methylation mark, how would you identify the HMT that is...
If you discovered a new histone methylation mark, how would you identify the HMT that is responsible for adding this post-translational modification on histones?
A mutation has occurred in the DNA binding sequence for p53. The binding site is Pu-Pu-Pu-C-A/t-T/a-G...
A mutation has occurred in the DNA binding sequence for p53. The binding site is Pu-Pu-Pu-C-A/t-T/a-G Py-Py-Py; and is converted to Pu-Pu-Pu-T-A/t-T-A/t-T/a-G Py-Py-Pu in the promoter of the Mdm2 gene. What base would be methylated? What would be the effect of such a mutation on methylation ? What could be the effect of such a mutation on p53 binding? And, why? How would the expression of Mdm2 be affected ?
Some cancers have been treated with drugs that inhibit Histone deacetylases (HDACs). A. Explain how these...
Some cancers have been treated with drugs that inhibit Histone deacetylases (HDACs). A. Explain how these drugs might work. B. Do you think the cancer-causing genes that respond to the HDAC inhibitors are likely to be proto-oncogenes or tumor-suppressor genes? Explain your reasoning.
754. A mutation in the Lac repressor protein prevents it from binding to lactose. Will the...
754. A mutation in the Lac repressor protein prevents it from binding to lactose. Will the Lac operon be expressed when lactose levels are high and glucose levels are low? Explain your reasoning.
how would a GTPase activating protein inhibit Ras?
how would a GTPase activating protein inhibit Ras?
A mutation results in the failure of fibroblasts to move to the site of infection. It...
A mutation results in the failure of fibroblasts to move to the site of infection. It is discovered that this mutation causes a particular protein to be absent, which leads to premature actin mRNA translation. Which protein is most likely absent due to the mutation? CPEB general transcription factor ZBP1 (zip code-binding protein) Src Either Src or ZBP1
Normally the intact endothelium produces ________ and _________, which inhibit ______________.
Normally the intact endothelium produces ________ and _________, which inhibit ______________.
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT