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Under conditions where ketone bodies are being produced in the liver, how many ATPs can be...

Under conditions where ketone bodies are being produced in the liver, how many ATPs can be produced from a molecule of arachidic acid if all resulting molecules of acetyl-CoA are converted into β-hydroxybutyrate?

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Answer #1

Answer:

As the concentration of acetyl CoA builds up, the excess is converted in the liver to the ketone bodies acetoacetate, -hydroxybutyrate, and acetone.

These ketone bodies are carried by the blood to body tissue, mainly the brain, heart and skeletal muscles, where they may be oxidized to meet energy needs.

Under normal condition, the concentration of ketone bodies in the blood averages 0.5 mg/mL.

ATPs can be produced from a molecule of arachidic acid if all resulting molecules of acetyl-CoA are converted into β-hydroxybutyrate-

Arachidic acid (C20) -

(C2) Acetyl CoA = 10 12 = 120 ATP

Round of β-oxidation = 9

NADH = 9 3 = 27 ATP

FADH2 = 9 2 = 18 ATP

TOTAL ATP = 165 - 2 = 163 ATP

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