Question

High school chemistry class filtration using a flask and a paper disk filter is known as dead-end filtration. It is rarely used in biotech processes. Instead, crossflow filtration is used. Why?

Answer 1

Ans: Yes, Crossflow filtration is used in biotech process rather than dead end filtration. Cross-flow filtration (OR tangential flow filtration) is a type of filtration system used in the biotechnology manufacturing.

Cross-flow filtration has got its name because the majority of the feed flow travels tangentially across the surface of the filter, rather than into the filter.

It can be a continuous process, unlike batch wise in dead-end filtration.

A higher overall liquid removal rate is achieved by the prevention of filter cake formation.

Solids content of the product slurry may be varied over a wide range.

It is possible to fractionate particles by size in Cross Flow Filtration.

And the most important advantage of this process is that the filter cake is substantially washed away during the filtration process which increases the length of time that a filter unit can be operational.