Q3. In a village, if the proportion of individuals who have sickle-cell disease is 0.40, and the population is assumed to be at Hardy-Weinberg equilibrium, what is the expected frequency of the HbS allele? (Hint: What is the genotype of people with sickle-cell disease, and how is that genotype represented in the Hardy-Weinberg equation?)
0.80 0.63 0.20 0.16
Hardy-Weinberg equation
In every question, it is important to realize what data has been provided. The data will fit to either of the equations and it is important step to understand where the data lies.
We have the proportion of individuals provided, therefore the data is the genotype frequency.
So for this equation -We are provided- HbSHbS2(q2)=0.40
Allele frequency-HbSHbS(q)==0.63
The allele frequency =0.63
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