Question

True or False

31._____ Laminins are multidomain glycoproteins composed of a, b, and gpolypeptide chains.

32._____ Translocation between chromosomes 9 and 22 is responsible for chronic myelogenous leukemia.

33._____ Integrins can exist in two major activity states; inactive/folded and active/extended.

34._____ The Ig superfamily of cell adhesion molecules includes NCAM and ICAM.

35._____ The tumor microenvironment plays a significant role in tumorigenesis.

Answer 1

31. True

Laminins are multidomain glycoproteins composed of a, b and g polypeptide chains.

Laminins are a type of heterotrimeric proteins containing alpha chain, beta chain and gamma chain.

32. True

Translocation between chromosome 9 and 22 is responsible for chronic myelogenous leukemia.

It impairs physiological signalling pathways and also disrupts the genomic stability.

33. True

Integrins can exist in two major activity states; inactive/folded and active/extended.

Inactive/folded are of the low affinity and active/extended are of the high affinity.

34. True

The Ig superfamily of cell adhesion molecules include NCAM and ICAM.

35. True

The tumor microenvironment plays a significant role in tumorigenesis.