Question

Which ONE of the following occurs when a person with type I diabetes fasts for too...

Which ONE of the following occurs when a person with type I diabetes fasts for too long without injecting insulin?

Choose the best answer

The rate of ketone body synthesis in the liver decreases.

The rate of glycogen synthesis in the liver increases.

The rate of gluconeogenesis in the liver increases.

The rate of glycolysis in the liver increases

The rate of fatty acid synthesis in the liver increases.

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Answer #1

Type 1 diabetes is a chronic disease in which the immunu system of our body destroys insulin making cells in the pancreas. These cells are called beta cells and produces insulin which is a hypoglycemic hormone and it reduces the blood glucose levels. So, patients with diabetes 1 are completely dependent on insulin injections because the body is unable to make insulin. In patients with severe insulin deficiency, a prolonged fast in the absence of adequate insulin can lead to excessive glycogen breakdown and increased gluconeogenesis and ketogenesis, leading to hyperglycemia and ketoacidosis.

Therefore, when a person with type I diabetes fasts for too long without injecting insulin, the rate of gluconeogenesis in the liver increases. Hence, 3rd option is correct.

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