Question

From the list below, which of the following enzymes are needed to convert dUMP to dTTP?

I. dUTP Phosphatase

II. Thymidylate Synthase

III. Ribonucleotide Reductase

IV. Nucleotide-Diphosphate Kinase (NDK)

V. Thymidylate Kinase

Choose the best answer

I, II, and V

II, III, and V

II, III, and IV

II, IV, and V

I, III, and IV

Answer 1

The answer is II,IV,V.

Thymidylate synthase, thymidylate kinase and nucleotide diphosphate kinase(NDK) are the enzymes required for the conversion of dUMP to dTTP.