Suppose you had a strain of E. coli that has a nonsense mutation that renders the ftsH gene nonfunctional. What is the outcome of phage lambda infection in this strain? Explain.
The common function of ftsH protein that is secreted by E.coli when a phage lambda infection occurs is the cleavage of the CII protein of the phage lambds thereby initiating the lytic cycle in the lambda phage. If there is a nonsense mutation in this ftsH gene, then this CII degradation wont happen after phage lambda infection and hence the phage will undergo lysogenic cycle in the E.coli.
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