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What would happen to TRANSLATION if there was a mutation such that a UGA codon was...

What would happen to TRANSLATION if there was a mutation such that a UGA codon was changed to UCA? Explain your reasoning.

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Answer #1

UGA is a stop codon which signals the ribosome to stop the translation process. UCA codon codes for the amino acid Ser. If the mutation causes a stop codon to change into a normal codon, the translation process will continue further till another stop codon is found, resulting in a longer protein that normal. If another stop codon is not found within the DNA, the translation process will continue until the last codon at the 3' end of the mRNA. These kinds of proteins will not be able to function as usual.

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