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What would the consequences be for trp regulation if the leader sequence were deleted?

What would the consequences be for trp regulation if the leader sequence were deleted?

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Answer #1

Q.What would the consequences be for trp regulation if the leader sequence were deleted?

Answer: When the level of tryptophan in the environment is high, the trp operon is inactive (switched 'off'). Trp operon is active (switched 'on') when there is a condition in the cell to synthesize the tryptophan all by itself (level of tryptophan is low in the environment).

The leader sequence of trp operon are the RNA element which forms secondary structures to signal RNA polymerase to terminate transcribing when trp operon is switched 'on'(when trpytophan is now sufficiently available in the cell). Deletion of such sequence may result in unstable transcription.

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