For the following questions (4-6), make a diagram summarizing the main steps in cellular respiration (glycolysis, pyruvate oxidation, Krebs cycle, electron transport chain, chemiosmosis, fermentation) indicating the inputs and outputs of each process. This diagram will help you answer the questions.
1- Based at the diagram you drew, answer the following questions: A) How much energy is harvested in glycolysis (use ATP and potential ATPs as metric)? B) When is the oxidation of the glucose molecule completed? Explain what indicated that. C) What part/component of the glucose molecule is used in the electron transport chain? D) How does the electron transport chain contribute to ATP production?
2- Cyanide poisoning causes a type of hypoxia by inhibiting cytochrome c oxidase, which is the very last protein in the electron transport chain.
3- Explain how/why cyanide inhibition of cytochrome c oxidase interferes with cellular respiration. B) Does the cell have any alternative to keep glycolysis going? C) Explain the purpose of oxygen in respiration. A) Explain what would happen to ATP production in a mitochondrion that has “leaky membranes”, which would allow protons to diffuse through. B) Explain how the proton gradient contributes to ATP production.
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