Question

Malignant cancer cells tend to have all of the following EXCEPT __________.

Select one:

- reduced binding

- reduced tendency for apoptosis

- increased rate of mitosis

- reduced dependence on external signals

- reduced expression of telomerase

Answer 1

Option 5 is correct. Reduced expression of telomerase.

In malignant cancer there is no reduction of telomerase expression. If there is no telomerase then cell division will stop

Telomerase restores short bits of DNA known as telomeres, which are otherwise shortened when a cell divides via mitosis. In normal circumstances, where telomerase is absent, if a cell divides continously, at some point the progeny reach their Hayflick limit, which is believed to be between 50–70 cell divisions.