If a mitochondria began leaking cytochrome c because of free radical production and became severely damaged how would the cell deal with this issue?
Select one:
- Release inhibitors
- Initiate Necrosis
- Inactivate proliferation
- stop making ATP from electron transport
- Initiate Apoptosis
Ans. Cytochrome C that is found in the inner membrane of mitochondria plays a vital role of shuttling electrons via the respiratory chain, between complexes IIII and Complexes IV and also in cell apoptosis. In the mitochondrial inner membrane there is a lipid called cardiolipin, to which Cytochrome C binds,thus preventing it from releasing out of the mitochondria and initiate apoptosis. When these Cytochromes C starts to leak,it starts entering the cytosol, thus initiating apoptosis.
Hence,the answer is 'Initiate Apoptosis'.
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