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How is it possible for a father who is a carrier of Cystic Fibrosis (CF) and...

How is it possible for a father who is a carrier of Cystic Fibrosis (CF) and A healthy mother to potentially have a child with CF?

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Answer #1

Children may be born with cystic fibrosis if 2 parents carries one faulty gene for the disease. But, when a mutated CFTR gene is inherited from father and a normal CFTR gene is inherited from the mother, the offspring will be a cystic fibrosis carrier. Cystic fibrosis carriers are generally healthy, but they can pass the mutated gene to their children.

Therefore, an individual must be inherit two non-functioning CF genes one from each parent. Cystic fibrosis is a recessive condition, which means that to have CF in children, must inherit two copies of the gene, one from each parent.

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