Question

Flag this Question Question 491 pts A neutral missense mutation is a mutation that Group of...

Flag this Question

Question 491 pts

A neutral missense mutation is a mutation that

Group of answer choices

Gives rise to another codon, which nonetheless specifies the same amino acid

Gives rise to another codon, which specifies a chemically similar amino acid (so that protein function remains unaffected)

Gives rise to another codon, which is not translated

Flag this Question

Question 501 pts

Consider the following codon for lysine: 5’-AAA-3’. The DNA is mutated in such a way that this codon becomes 5’-UAA-3’. Such a mutation could be characterized as

Group of answer choices

Transition; missense

Transition; nonsense

Transversion; missense

Transversion; nonsense

Flag this Question

Question 511 pts

Which of the following wobble pairs makes a larger contribution to spontaneous mismatch mutations in DNA?

Group of answer choices

AT

CC

GC

GT

Flag this Question

Homework Answers

Answer #1

Answer::

(491)Give rise to another amino acids which specifies chemically similar amino acid( so that protein function remain unaffected)

(501) Transversion,nonsense mutation

(511) GT

Explanation:::

#As we know genome are not a static entity,it is dynamic in nature and a sudden heritable change in the genetic material give rise to alternative form of any gene termed as mutation.Mutation can be spontaneous or induced.Spontaneous mutation occur without involvement of mutagens ,it occur because of replication error, spontaneous lesions and transposition of transposable elements during the normal growth of cells.

Normally DNA replication to gives DNA then transcribe to RNA and it translates into proteins ( amino acids).when mutation occur in the DNA sequence it affects the RNA sequences and amino acids also.

DNA--RNA---proteins

Some genetic codon coded for same amino acids because we have 20 amino acids and 64 genetic codon...so when there is mutation occur in the sequence but after translation it will give same amino acid ,it termed as silent mutation...but in some cases the mutation occur in the amino acid sequence gives rise to different amino acid sequence but the chemical nature will be same as it does not affects the functioning of protein ...it termed as Neutral missense mutation.For example..the change of AAA( lysine) to AGA ( arginine), both amino acid are chemically basic in nature so after mutation as proteins function are equivalent.

##Normally DNA has 4 base sequences A,G,C,T in which purine contain adenine(A) , guanine(G) and pyrimidine has cytosine (C)and thymine(T).In mutations when purine bases replace with purines means A--G or Pyrimidines bases replace with Pyrimidines means C--T ,it is called transition...whereas when Purine bases replace with pyrimidines such as A--T or G---C is called Transversion. In the given question A is replaced with T means purine bases replace with Pyrimidines..so it is Transversion....and in genetic codon three sequence UAA,UAG,UGA are known as stop codon/ termination codon responsible for shortening the protein length by stopping the translation.In a mutation ,if amino acid sequence coded any of three sequence then it is called nonsense mutation.In this sequence we get UAA after mutation so it is nonsense mutation.

## When A pair with T and G paired with C it is called Watson crick pairings but sometimes it is not paired as naturally occur due to mutation then G pairs with T because of their stable keto enol formation or A pair with C imino to enol state which is not stable.Wobble pairing is normally occur in the last(3rd position) sequence of amino acid which doesn't affect the nature of amino acid because 1st two pair are the same as required.

So, mostly GT transition is responsible for DNA mismatch mutation due to keto enol formation.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Flag this Question Question 411 pts When an electron is transferred from one atom to another,...
Flag this Question Question 411 pts When an electron is transferred from one atom to another, and the two atoms are then electrically attracted to one another, a(n) ________________ bond is formed. ionic kinetic covalent hydrogen Flag this Question Question 421 pts Changing the number of ____________ of an atom would change the chemical properties of the atom. neutrons protons electrons electron shells Flag this Question Question 431 pts Forming molecules and breaking down molecules in biological organisms usually requires...
If the guanine (G) in the DNA sequence 3’ TTACGTTTC is deleted, what are the first...
If the guanine (G) in the DNA sequence 3’ TTACGTTTC is deleted, what are the first 2 amino acids that will be joined at the ribosome? Remember there is a START codon. Use the information on this chart to answer the question. asparagine, alanine methionine, glutamine leucine, glycine leucine, phenylalanine methionine, lysine The mutation in the above question is an example of a ________________ mutation. Group of answer choices frameshift nonsense missense silent
Flag this Question Question 482 pts Proteins of the Electron Transport System are: Group of answer...
Flag this Question Question 482 pts Proteins of the Electron Transport System are: Group of answer choices embedded on the bacterial cell membrane located in the cytoplasm of the cell embedded on the bacterial cell wall none of the above Flag this Question Question 492 pts Over 90% of the strains of this species are resistant to penicillin Group of answer choices Escherichia coli Vibrio cholera Staphylococcus aureus Salmonella typhimurium Flag this Question Question 502 pts Which of the following...
Fatty acid biosynthesis involves: malonic acid. Group of answer choices True False Flag this Question Question...
Fatty acid biosynthesis involves: malonic acid. Group of answer choices True False Flag this Question Question 1211 pts Fatty acid biosynthesis involves: malonyl CoA. Group of answer choices True False Flag this Question Question 1221 pts Fatty acid biosynthesis involves: acyl carrier protein. Group of answer choices True False Flag this Question Question 1231 pts Fatty acid biosynthesis involves: coenzyme A. Group of answer choices True False Flag this Question Question 1241 pts Fatty acid biosynthesis involves: sulfhydryl groups. Group...
A portion of a protein-coding gene is provided for this question. Given the non-template DNA sequence...
A portion of a protein-coding gene is provided for this question. Given the non-template DNA sequence of 5'-TACTATGCTGAGCATTATTGCTAAGTGATGGCTA-3': a. Write the complementary template DNA sequence in a 5' to 3' direction. b. Write the mRNA sequence that would be transcribed from this segment of DNA in a 5' to 3' direction. c. Starting from the first start codon, write the polypeptide sequence that would be translated from the mRNA sequence. d. Define the following terms in your own words: frameshift...
Question 401 pts Kinetic energy is the stored energy that can be used for motion. True...
Question 401 pts Kinetic energy is the stored energy that can be used for motion. True False Flag this Question Question 411 pts When an electron is transferred from one atom to another, and the two atoms are then electrically attracted to one another, a(n) ________________ bond is formed. ionic kinetic covalent hydrogen Flag this Question Question 421 pts Changing the number of ____________ of an atom would change the chemical properties of the atom. neutrons protons electrons electron shells...
1- Which of the following statements about the use of synthetic polynucleotides in cracking the genetic...
1- Which of the following statements about the use of synthetic polynucleotides in cracking the genetic code is true? Group of answer choices Particular codons are generated in predictable ratios with random RNA polymers containing specific ratios of different nucleotides. Poly(A) RNA directs the synthesis of only polylysine in vitro. Three different amino acids are incorporated into peptides when synthetic polymers of only one nucleotide are used to synthesize the RNA primer. The codon table was completed by using RNA...
Question 82 pts Under the UCC, output and requirements contracts are illusory. Group of answer choices...
Question 82 pts Under the UCC, output and requirements contracts are illusory. Group of answer choices True False Flag this Question Question 92 pts Modern contract law has fewer exceptions to the consideration requirement than classical law did. Group of answer choices True False Flag this Question Question 102 pts Agreeing to give up a valid legal claim against another party can be consideration. Group of answer choices True False Flag this Question Question 112 pts Accord and satisfaction only...
Question 112 pts Accord and satisfaction only applies to liquidated debts. Group of answer choices True...
Question 112 pts Accord and satisfaction only applies to liquidated debts. Group of answer choices True False Flag this Question Question 122 pts Which of the following is an exception to the consideration requirement? Group of answer choices All of these Promissory Estoppel Promises to pay debts whose enforcement is barred by the statute of limitations Charitable subscriptions Flag this Question Question 132 pts Illusory promises have no consideration because they do not have "legal value." Group of answer choices...
Question 111.5 pts Which of the following are examples of tools used in motion study? Group...
Question 111.5 pts Which of the following are examples of tools used in motion study? Group of answer choices A. Charting B. Therbligs C. Work Sampling D. A and B only E. A, B and C only Flag this Question Question 121.5 pts In master scheduling, the term for a time period’s uncommitted inventory is: Group of answer choices A. Ending on-hand inventory B. Available-to-promise inventory C. Lead-time inventory D. Cycle stock inventory E. None of the above Flag this...