Question

A mutation is found in the gene that codes for the Lacl repressor protein gene. The...

  1. A mutation is found in the gene that codes for the Lacl repressor protein gene. The protein no longer performs its intended function. Explain what would be the outcome at the gene level and for the E coli. Could you please explain this answer in detail.

Homework Answers

Answer #1

The Lac I gene is not a part of the Lac operon but is essential for its expression. The Lac Operon activity is regulated by the repressor protein which binds to the operator site thus, not allowing the transcripton process to occur and hence, no lactose gets produced when it is available in the enviornment. Thus there is no excessive production of the lactose. However, when there is a mutation in the Lac I gene, the production of the repressor protin which is encoded by the same gene doesn't happen. This in turn, interferes with the regulation of the lactose operon.

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