Question

The numerical expression of the ω-3 fatty acid having 14 carbon atoms and 3 double bonds is ().

In the fatty acid synthesis, () is used as a substrate, and when one molecule of fatty acid with carbon number N (even integer) is newly synthesized, the substrate is () molecule, coenzyme () is () molecule, and ATP is () The molecule is used.

On the other hand, when the same fatty acid is decomposed by β-oxidation, first, fatty acid acyladenylic acid is formed from () and fatty acid, and () is generated before the cyclic oxidation is initiated, and then fatty acid acyladenylic acid is generated. Reacts with () to form fatty acyl CoA and () goes out. After this fatty acid acyl CoA is produced, the cyclic oxidation reaction proceeds, and () molecules of the total fatty acid synthesis substrate are produced from one molecule of fatty acid, and reducing cofactors () [if There are multiple answers enumerate them in alphabetical order].

fill in the ()

Answer 1

The numerical expression of the ω-3 fatty acid having 14 carbon atoms and 3 double bonds is (Δ7c, Δ9c, Δ11c).

In the fatty acid synthesis, acetyl Co-A is used as a substrate, and when one molecule of fatty acid with carbon number N (even integer) is newly synthesized, the substrate is 8 molecule, coenzyme NADPH is 14 molecule, and ATP is 7 molecule is used.

On the other hand, when the same fatty acid is decomposed by β-oxidation, first, fatty acid acyladenylic acid is formed from ATP and fatty acid, and inorganic phosphate is generated before the cyclic oxidation is initiated, and then fatty acid acyladenylic acid is generated. Reacts with free coenzyme A to form fatty acyl CoA and AMP goes out. After this fatty acid acyl CoA is produced, the cyclic oxidation reaction proceeds, and 8 (eight) molecules of the total fatty acid synthesis substrate are produced from one molecule of fatty acid, and reducing cofactors FAD and NAD+.