Question

Why would an antifungal drug do little to reduce the effects of a fungal toxicosis?

Answer 1

The Antifungals comprise a large and diverse group of drugs used to treat fungal infections.Many of the systemic antifungals are toxic to mammalian cells, especially amphotericin B. Topical antifungals, in contrast, have little systemic toxicity because of poor absorption through the skin.
The mechanisms of action of Antifungals include inhibition of fungal membrane and cell wall synthesis, alterations of fungal membranes, effects on microtubules, and inhibition of nucleic acid