Question

In DNA replication, what is the difference between replicating the leading versus the lagging DNA strands?

Answer 1

Leading strand replication	lagging strand replication
Synthesized continuously	synthesized discontinuously in small fragments known as Okazaki fragments.
the opening of double helix occurs in 3' to 5' direction	the opening of double helix occurs in 5' to 3' direction
grows in 5' to 3' direction	grows in 3' to 5' direction
elongation starts at the beginning of replication	elongation occurs a bit later after initiation of replication
grows towards the replication fork	grows away from replication forks
does not require DNA ligase	requires DNA ligase to join the Okazaki fragments
replication occurs with high speed	replication is slow compare to the lagging strand