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What is consanguineous marriage? Why is the appearance of genetic disease more probable in the offspring...

What is consanguineous marriage? Why is the appearance of genetic disease more probable in the offspring of a consanguineous marriage?

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Consanguineous merriage is define as the marriages between the biologically or blood related people i.e marrying first or second cousin.Offsprings of consanguineous unions expected to have identical genes from both parents resullts in higher inbreeding coefficient (biological similarity).

The offspings of consanguineous marriage are more prone to autosomal disorder due to expression of mutated inherited recessive gene from both parents.These recessive alleles are sometime lethal to the offsprings as a result increase the mortality rate among infants.Due to inbreeding coefficient 1 there are 100 percent chances of getting similar genes from both parents.

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