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A one-year old child is discovered to have numerous bone fractures. Social workers suspect child abuse....

A one-year old child is discovered to have numerous bone fractures. Social workers suspect child abuse. What condition might lead to a false conclusion about this child? Explain what causes this developmental disorder. How common is it?

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The two most frequently recognised disease processes causing bone fragility in infancy are metabolic bone disease of prematurity and osteogenesis imperfecta. The main other causes of bone fragility are metaphyseal dysplasias, calcium-phosphorus metabolism disorders, and preterm birth as well as vitamin D deficiency.

Osteogenesis Imperfecta is a group of genetic disorders caused in 95% of cases by mutations in the collagen type 1 gene. Osteogenesis Imperfecta has been estimated at 1/10,000 to 1/20,000.

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