Which is not consistent with double helical structure of DNA?
(a) A = T, C = G
(b) density of DNA decreases on heating
(c) A + T/C + G is not constant
(d) both a and b.
Ans) Option A) A =T, G=C follows Chargaffs rule. This rule is consistent for double helical structure of DNA.
Option C) This given option is wrong as A + G / C+T = 1. As it follows Chargaffs rule.
The correct option for this question is option B) density of DNA decreases on heating.
Explanation:- On heating of the dsDNA the double hellical structure breakdown into single stranded DNA due to meltdown of the hydrogen bond between the bases. The optical density of ssDNA is greater than the ds DNA. This confirms that density of DNA inceases on heating.
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